【应用】发生器和电极针在射频消融领域的应用之肿瘤篇

时间： 2019-07-31 来源：Rosenberger

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在肿瘤领域，射频消融主要用于实体器官瘤，包括肝肿瘤、转移的结肠癌、早期肺癌、肾细胞癌、骨转移癌、骨癌、乳腺癌等等。根据不同的应用，其对应的作用于病灶的电极针设计各不相同。目前射频消融在实体肿瘤中的消融，有两种方式到达目标病灶。一是经皮穿刺，通常设计成硬针；二是经人体已有通道（如消化道，呼吸道，主动脉，桡动脉），通常设计成软管针。根据入针的方式不同，针的设计要求也不同。整个消融平台部件主要包括发生器、电极针、水泵。

发生器：频率范围：350KHz-500KHz，单端口200W左右

电极针：正负极，根据具体应用设计成分离的，或集合到同一电极针

水泵：冷却电极针，目前主流的有水冷以及气冷。

下面将对该平台中最重要的部分：发生器和电极针做技术分析。

1、发生器技术实现

主机的设计主要有信号源、功率放大模块、控制模块、温度监控模块、阻抗监控模块，目前市面比较主流的反馈控制为温度或阻抗监控，通过时时动态监控两个极之间的阻抗，或者发射端作用于病灶的针杆处组织的温度，反馈给发生器功率控制模块，根据所测的电阻或温度控制功率发射大小和作用时间。

在回路设计方式上，一种是系统中电极针为单独的接地板，通过两个极板之间的阻抗控制射频能量的输出，如下图所示，人体将作为整个回路的一部分，主机与接地板共地。

另一种方式是两极整合到同一个电极针杆的设计，通常通过测试针杆附近组织温度来控制射频能量的输送，见下图。

在主机的设计中，主机的输出通常集合射频输出能量端口、温度和阻抗监控等通路连接。罗森伯格可以提供信号源与功率放大模块的高性能连接解决方案，也可以根据客户的需求，提供定制化的连接解决方案。

2、电极针技术实现

该部分主要包括接地板、射频测温线缆组件和辐射针体设计。

接地板：

接地板一端通过导线与主机接触，另外一端与人体皮肤接触（和皮肤接触的部分含有导电胶），通过导电胶与皮肤接触，和人体形成一个闭环回路。罗森伯格可以提供该部分的线缆设计及生产。

射频及测温线缆组件：

辐射针体中线缆组件包含射频电缆、温度测试线以及对应的混装接头，罗森伯格可以根据客户的需要，提供订制化的设计。

辐射针体设计：

在硬针设计上，经皮穿刺的电极针要求针体有足够的刚性，针尖的设计要足够锋利方便穿刺。目前主流硬体针设计有单极棒针、伞状针，并可配合穿刺针等辅助器械使用，常见辐射针头设计方案如下图：

在软导管针设计上，要求该类型软体针不仅柔软，同时具有一定韧性以及可操作性。目前比较主流软针应用为肺癌消融，该类针体本身除了消融，还具有单独通道结合电磁导航。该类型的电极针结构如下图：

此类针的设计难点在于针体要求越来越细，而可承受的功率却越来越大，同时兼具可操作性，导致生产难度越来越大，如何从设计上保证平衡是未来发展的重点。依托六十余年的射频技术积淀，罗森伯格不仅能够提供整体的线缆及接头组件的设计和生产，也可根据客户需求提供传输大功率的定制化微细电缆。

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本文由宝丁转载自Rosenberger，原文标题为:罗森伯格在射频消融领域的应用之肿瘤篇，本站所有转载文章系出于传递更多信息之目的，且明确注明来源，不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。

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【选型】Rosenberger（罗森伯格）射频连接器/电缆组件/转接器/校准件选型指南

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型号- L06-C120-XXX,3GK0KS-010,09KR121-K0AS3,03K760-S23N5,LA3-C017-XXX,LA1-C359-XXX,LU8-005-XXX,L72-C484-XXX,LU7-C484-XXX,LA1-C006-XXX,05K150-C10S3,03S12L-000S3,L07-C370-XXX,53AS105-K20N3,05S12L-000S3,53AS120-K06N3,LA3-C041-XXX,LU7-031-XXX,02K118-S00S3,53AS102-K01N3,RG214/U,05CK010-150,L73-C067-XXX,09KR102-S0AS3,RG142 B/U,LU7-039-XXX,03AS102-K03S3,60W000-003,02K220-UBR,RTK162P,L07-C202-XXX,LU1-006-XXX,32AS102-K20S3,LU7-C340-XXX,08K121-K00S3,LU7-C082-XXX,02AS102-K20S3,LA3-C064-XXX,02S121-K00S3,RTK-FS 250-FEP-C,L72-C333-XXX,32S153-K00L5,L71-C717-XXX,LU5-C247-XXX,L70-280-XXX,LU7-C347-XXX,02KR121-S0AS3,03K717-S22S3,19S15R-001E4,59CK100-150,08AS102-K03S3,RTK-161,RTK-162,L70-278-XXX,03K717-S22S5,LU7-C339-XXX,09CK001-150,32K120-UBR,LU5-C209-XXX,L08-C316-XXX,L99-923-XXX*,53S17R-020N3,03K728-S22S3,L73-C108-XXX,L08-C002-XXX,05AS102-K10S3,L72-C301-XXX,LU1-C086-XXX,RTK-FLEX 405,LU7-069-XXX,RTK-FLEX 402,02AS102-K40S3,53S101-K00N5,03K706-S24S3,RTK080,32S105-K00L5,LU8-006-XXX,LU7-C564-XXX,LU7-C1090-XXX,LU7-C051-XXX,L99-816-30G,L99-816-30F,53AS110-K03N3,03K30R-MSOS3,08AS102-K06S3,32AS102-K10S3,LU8-C043-XXX,03W021-000,L99-816-30E,L99-816-30D,02KR121-SR00S3,02K80F-40ML5,L07-C371-XXX,LU7-C668-XXX,09KR105-K0AS3,53S132-K00L5,RG216/U,53AS102-K03N3,32K101-K00L5,02KR105-K0AS3,03AS122-K20S3,LA2-C120-XXX,LA2-C199-XXX,53AS105-K30N3,RG 59,L71-C716-XXX,LA2-C190-XXX,08KR121-SR00S3,03K121-K20S3,32K140-419,LU7-C331-XXX,LU1-005-XXX,02CK020-150,L73-C060-XXX,L07-C376-XXX,74CK010-170,32K15R-001E3,53S17R-010N3,LU1-022-XXX,08K30R-MSOTS3,09AS102-K40S3,LA1-C142-XXX,02S121-S20S3,08K80F-40ML5,LA3-C138-XXX,R53K153-S61N1,L08-C003-XXX,LU7-C346-XXX,RTK081,53S101-S00N5,03K710-K22S3,53AS102-K02N3,L08-C315-XXX,RTK-FS 250,05GK0KS-010,L71-C275-XXX,08S121-K00S3,LMR 195,RTK 162,53S101-115N5,R53K165-S61N1,LA3-C132-XXX,RTK 040,RTK 161,03S150-C10S3,RTK 047,L07-C372-XXX,L20-001-XXX,03AS102-K10S3,LU5-C102-XXX,07CK100-150,03K719-S60S3,LU7-C342-XXX,09CK010-150,53AS110-K20N3,09K121-K20S3,08CK001-150,L72-C923-XXX,01K80A-40ML5,RTK 052,RTK 050,64K30R-MSOTS3,09S121-K00S3,01W021-000,53AS102-K20N3,53K15R-005N3,05S30R-MSOS3,LA3-C305-XXX,LU7-C667-XXX,74CK001-170,L08-C314-XXX,53AS110-K10N3,02S17R-001D3,32S15R-0.5E3,02S30R-MSOS3,05AS122-K20S3,53AS102-K30N3,02K320-599,05AS102-K03S3,RG 59 B/U,L08-C004-XXX,06W021-000,R53K160-S61N1,60S101-K50N1,07GK0KS-010,09S121-S20S3,LU1-025-XXX,03KR107-P0AS3,LA1-C099-XXX,L07-C204-XXX,LA1-C361-XXX,LU7-C345-XXX,L71-C276-XXX,LU5-C103-XXX,18S15R-0.5E3,LU1-045-XXX,53AS105-K10N3,03KR121-S0AS3,03K764-S22D3,P5CK010-170,LU7-C343-XXX,28CK100-150,RTK 081,53AS102-K10N3,32W100-016,L71-C282-XXX,05AS122-K40S3,09KR102-K0AS3,06CK010-150,RTK161P,05AS102-K06S3,L07-C207- XXX,09S121-S00S3,LA3-C103-XXX,LA3-C232-XXX,LU7-C337-XXX,32S17B-1.0E3,03AS102-K20S3,32AS102-K03S3,L72-C924-XXX,LU5-C210-XXX,L17-C002-XXX,09KR121-SR00S3,02AS122-K20S3,53QCK10A-150,L08-C313-XXX,LU1-C020-XXX,L70-279-XXX,09AS102-K06S3,LU8-C018-XXX,03AS102-K30S3,53K17R-010N3,RG 142,03S17R-001D3,53AS120-K03N3,MR 195,03CK010-150,07W021-000,LU7-C350-XXX,L71-C197-XXX,09K121-K00S3,28S1ER-001N5,03K150-C10S3,09S121-K20S3,08S30R-MSOTS3,05CK001-150,03S30R-MSOS3,08S121-S00S3,LU7-C009-XXX,L07-C203-XXX,05K30R-MSOS3,07CK120-150,32K084-051,19CK010-150,03S121-S20S3,RTK-FLEX 405-SPCCS-FEP,LU7-043-XXX,L17-C001-XXX,LU7-C344-XXX,09CK020-150,L07-C206-XXX,09AS102-K03S3,L99-921-XXX*,02S108-S00S3,02K121-K20S3,LA3-C231-XXX,LU1-034-XXX,03K12S-000S3,02CK001-150,03S30R-MSOTS3,03KR121-K0AS3,LU1-003-XXX,LU5-C236-XXX,L08-C545-XXX,L06-C003-XXX,53S17R-005N3,51CK010-150,32K17R-001E3,01CK120-150,L72-C925-XXX,32S103-S00L5,5GK0KS-010,02KR107-P0AS3,L09-C001-XXX,LU7-C665-XXX,03S109-S00S3,05K12S-000S3,LA2-C221-XXX,53AS120-K20N3,08KR121-K0AS3,02AS102-K06S3,RG 223,53AS105-K06N3,02K30R-MSOTSE,53W011-000,03AS102-K40S3,L08-C320-XXX,LU7-035-XXX,32AS102-K06S3,51S1RR-001N4,60GK0KS-010,02AS122-K40S3,L08-C319-XXX,53AS110-K30N3,L07-C215-XXX,03S109-K00S3,LA2-C125-XXX,02K30R-MSOS3,RG 214,08AS102-K10S3,05AS102-K40S3,02K109-S00S3,LU7-C604-XXX,RTK 125,08GK0KS-010,P5GK0KS-010,LU5-C101-XXX,LU1-C134-XXX,LU1-004-XXX,08K400-383,09KR107-P0AS3,03S121-K00S3,02K243-40ME3,53AS105-K03N3,02AS102-K03S3,08K243-40ME3,03K705-S23S3,03K17R-001D3,60K101-K50N1,LA2-C163-XXX,02S108-K00S3,64K36R-MSOS3,32K100-039,L06-C117-XXX,53AS120-K10N3,28K1ER-001N3,08CK010-150,LA1-C115-XXX,03W008-000,05CK020-150,51CK100-150,70U-08S1-W1K1-XXXXXX,L72-C926-XXX,03CK001-150,R53S131-C02N5,RG 223/U,L07-C205-XXX,18K15R-0.5E3,RTK 106,LU7-C664-XXX,L08-C321-XXX,08K30R-MSOS3,08AS102-K20S3,03K705-S24S3,08KR121-S0AS3,03K721-S23S3,L71-C674-XXX,LA3-C191-XXX,L09-C006-XXX,03KR105-S0AS3,09KR105-S0AS3,03K121-K00S3,L08-C318-XXX,LU7-C326-XXX,70U-18K1-W1K1-XXXXXX,03K719-S22S3,RG 216/U,LU8-C042-XXX,53K15R-020N3,05AS102-K30S3,L99-815-30G,08CK020-150,03CK020-150,L07-C208-XXX,L99-815-30F,53S160-K50N1,L99-815-30E,L99-815-30D,09AS102-K10S3,LU7-C349-XXX,LA1-C052-XXX,03AS102-K06S3,53S17R-001N3,LU7-056-XXX,02K108-S00S3,L73-C061-XXX,RTK 092-70,60CK010-150,RTK052,03K30R-MSOTS3,RTK050,05K12L-000S3,02S109-K00S3,05S150-C10S3,53K15R-010N

2020年6月 - ROSENBERGER - 选型指南 - 第一版代理服务技术支持现货查询批量订货

Rosenberger最新提供各种长度的SMP和Mini SMP弹性接头，标称工作初始长度为12.35mm

Rosenberger提供各种长度的SMP和Mini SMP弹性接头，标称工作初始长度为12.35mm。由于其弹簧加载设计，这些接头——两侧的插孔配置——补偿了板对板应用中的距离公差，而不会降低射频性能，并在所有指定的x、y和z未对准情况下保持恒定的信号完整性。

2023-04-28 - 新产品代理服务技术支持现货查询批量订货

【IC】思为无线新品低噪声FEM功率放大模块PA01F39，邮票孔封装设计，输出功率可超过39dBm

G-NiceRF新品PA01F39模块是一款工作频率为400-480MHz的高性能FEM功率放大模块，集成了多项射频功能。该模块内置功率放大器（PA），支持输入功率达30dBm，输出功率可超过39dBm，同时包含低噪声放大电路（LNA）和天线开关。其邮票孔封装设计，小巧紧凑，便于嵌入式集成，大幅降低了用户开发大功率无线模块的难度，简化设计流程，提升开发效率。

2024-11-19 - 产品代理服务技术支持现货查询批量订货

RosenbergerHSD® Connectors High Speed Data Connector System

目录- Company Profile RosenbergerHSD® Product Overview RosenbergerHSD® Number Codes/Coding RosenbergerHSD® Technical Data RosenbergerHSD® Connectors RosenbergerHSD®+ Power Pin Connectors RosenbergerHSD®t Technical Data RosenbergerHSD®t Connectors Test Components & Tools Cable Assemblies Technical References Index

型号- D4W0A6-1D5,D4S24D-400A5-Y,D4S2UY-400A5-Y,D4S2UY-40MA5-Y,LD5-214-XXXX-Y-Y,D4K14A-1D5A5-Y,LAF-221-XXXX-Y-Y,LD9-205-XXXX-Y-Y,LAF-227-XXXX-Y-Y,LD9-214-XXXX-Y-Y,D4W001-000,LD5-229-XXXX-Y-Y,D4S10A-1D5A5-Y,99S16D-1D5A5-Y,99S21L-40MA5-Y,LAF-209-XXXX-Y-Y,LAF-203-XXXX-Y-Y,D4S21J-40MA5-Y,LD5-101-XXXX-Y-Y,LAF-212-XXXX-Y-Y,LAF-218-XXXX-Y-Y,D4S10V-40MA5-Y,LAF-230-XXXX-Y-Y,LD5-106-XXXX-Y-Y,D2S10A-1D9A5-Y,D4S20Y-400A5-Y,99S15A-1D5A5-Y,59W011-000,LAF-226-XXXX-Y-Y,D4W003-000,LAF-231-XXXX-Y-Y,LD5-219-XXXX-Y-Y,LAF-208-XXXX-Y-Y,LD9-213-XXXX-Y-Y,LD9-106-XXXX-Y-Y,D4K2LE-1D5A5-Y,LD5-107-XXXX-Y-Y,D4S23L-40MA5-Y,LD9-101-XXXX-Y-Y,D4K25L-1D5A5-Y,LD5-102-XXXX-Y-Y,LAF-202-XXXX-Y-Y,LD9-107-XXXX-Y-Y,D4W0A8-1D5,LXX-101-XXXX-Y-Y,D4K20C-1D5A5-Y,D2S10A-1AQA5-Y,LAF-220-XXXX-Y-Y,LAF-219-XXXX-Y-Y,99S10R-40MA5-Y,LD5-232-XXXX-Y-Y,D4W006-000,LAF-103-XXXX-Y-Y,D4K10A-1XXA5-Y,LD5-105-XXXX-Y-Y,LAF-207-XXXX-Y-Y,D2S14A-1D9A5-Y,LAF-213-XXXX-Y-Y,LD5-108-XXXX-Y-Y,LD9-203-XXXX-Y-Y,D4K2RE-1D5A5-Y,LD9-108-XXXX-Y-Y,LD5-218-XXXX-Y-Y,LD5-222-XXXX-Y-Y,LD9-105-XXXX-Y-Y,D4K10A-K00A5-Z,LAF-229-XXXX-Y-Y,LD9-218-XXXX-Y-Y,D4S14D-40MA5-Y,LD5-227-XXXX-Y-Y,LD5-213-XXXX-Y-Y,99S10L-40MA5-Y,D4K25R-1D5A5-Y,LAF-211-XXXX-Y-Y,D4K10C-1D5A5-Y,LD5-230-XXXX-Y-Y,59W010-000,LD9-103-XXXX-Y-Y,LD5-216-XXXX-Y-Y,LD5-224-XXXX-Y-Y,99K2LK-1D5A5-Y,99S219-40MA5-Y,LAF-222-XXXX-Y-Y,LD9-222-XXXX-Y-Y,D4S20W-40MA5-Y,LAF-216-XXXX-Y-Y,D4W006-SET,D4W0B6-1D5,LD5-205-XXXX-Y-Y,D4W008-000,D4W0A3-1D5,LAF-205-XXXX-Y-Y,D4K101-1D5/40Z,D4S20P-400A5-Y,LD5-217-XXXX-Y-Y,D4K1UA-1D5A5-Y,LD5-211-XXXX-Y-Y,LD5-226-XXXX-Y-Y,D2K10A-1AQA5-Y,D2K25A-1D9A5-Y,LD5-220-XXXX-Y-Y,99K15A-1D5A5-Y,D4K20E-1D5A5-Y,LD5-104-XXXX-Y-Y,LD5-202-XXXX-Y-Y,LD9-217-XXXX-Y-Y,D4S2UL-40MA5-Y,LAF-206-XXXX-Y-Y,D4S12H-40MA5-Y,D4W002-000,99K20K-1D5A5-Y,LAF-224-XXXX-Y-Y,LAF-215-XXXX-Y-Y,99K2LL-1D5A5-Y,LD5-103-XXXX-Y-Y,LD9-221-XXXX-Y-Y,D4W004-000,LAF-214-XXXX-Y-Y,LD5-207-XXXX-Y-Y,LD9-201-XXXX-Y-Y,LAF-102-XXXX-Y-Y,D4S10A-400L5-Y,LD5-221-XXXX-Y-Y,D4K25A-1D5A5-Y,LAF-232-XXXX-Y-Y,LAF-225-XXXX-Y-Y,LD5-203-XXXX-Y-Y,LAF-101-XXXX-Y-Y,D2K10A-1D9A5-Y,D4S14A-1D5A5-Y,99K2UK-1D5A5-Y,LD9-202-XXXX-Y-Y,D4K14C-1D5A5-Y,LD5-208-XXXX-Y-Y,D4S2UG-400A5-Y,LAF-201-XXXX-Y-Y,D4S1EQ-S01A5-YY,LAF-204-XXXX-Y-Y,LD5-206-XXXX-Y-Y,D4W007-000,LD9-102-XXXX-Y-Y,99S23F-40MA5-Y,LD5-225-XXXX-Y-Y,LD9-206-XXXX-Y-Y,D2K20A-1D9A5-Y,LD5-215-XXXX-Y-Y,LD9-209-XXXX-Y-Y,LD5-209-XXXX-Y-Y,LD9-210-XXXX-Y-Y,D2K14A-1D9A5-Y,LAF-210-XXXX-Y-Y,LD5-231-XXXX-Y-Y,D4K2UE-1D5A5-Y,LD5-210-XXXX-Y-Y,99K15B-1D5A5-Y,D4K10D-1D5A5-Y,D4W0A6-SET,LD5-201-XXXX-Y-Y,LAF-217-XXXX-Y-Y,LD5-204-XXXX-Y-Y,D4S20G-400A5-Y,99K2RK-1D5A5-Y,PCB-L1501-SB,LAF-223-XXXX-Y-Y,D4K10A-1D5A5-Y,D4S20Y-40MA5-Y,LD5-212-XXXX-Y-Y,D4S23M-40MA5-Y,LD5-228-XXXX-Y-Y,D4S10P-40MA5-Y,LD9-104-XXXX-Y-Y,LAF-104-XXXX-Y-Y,99K11D-1D5A5-Y,LD5-223-XXXX-Y-Y,D4K20B-1D5A5-Y,D4S10E-40MA5-Y,D4S2UQ-40MA5-Y,LAF-228-XXXX-Y-Y

October 2020 - ROSENBERGER - 选型指南代理服务技术支持现货查询批量订货